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王晓玲

教授

机械装备与控制工程系
xiaoling@me.ustb.edu.cn

学位：博士
所在系所：机械装备与控制工程系
行政职务：无
办公地点：
办公电话：
电子邮箱：xiaoling@me.ustb.edu.cn
科研方向：计算编程、数值仿真模拟在工程上的理论研究和应用。专注于但不限于如下几个方向：图像处理、三维图形处理、计算力学、计算生物力学、计算细菌生物膜、计算材料相变、人工智能在生物计算上的应用、生物的三维虚拟模拟以及展示、生物信息大数据的计算、处理、可视化；计算生物学在功能材料、生物马达、石油开采、环境治理、生物降解、清洁能源、生物工程、慢性疾病防治、药物、化妆品和清洁品研制开发等方面的应用。常年招生：不限学科背景，但是喜欢编程、熟练应用编程计算解决各种工程问题的硕士、博士、以及具有实际工程项目经验的工程博士。

本科生课程：《自然界中的相变》双语课、《生物力学工程》双语课、《生物机械工程》双语课

研究生课程：《生物工程》双语课

教育经历：
1996.09-2000.07　北京理工大学应用力学系，学士
2000.09-2003.01　北京理工大学应用力学系，硕士
2003.01-2006.12　香港科技大学机械工程系，博士

工作经历:
2007.01-2007.12　香港大学医学院　博士后
2008.01-2012.07　12博BET官方网站　　讲师
2012.07-2017.07　12博BET官方网站　　副教授
2017.07-现在　　 12博BET官方网站　　教授
2018.07-现在　　 12博BET官方网站　　博士生导师
2013.02-2013.08　美国西北大学　　访问学者
2013.09-2014.02　美国哈佛大学　　访问学者

成果与荣誉：
2019年荣获12博BET官方网站第六届“研师亦友--我最喜爱的导师”荣誉称号。
先后主持国家自然科学基金委资助的青年项目、青年面上连续项目，面上项目，重点国际合作与交流项目子项目5项，以及北京市、高校和其他项目。

代表性论著:
1.Xianyong Li, Rui Kong, Jiankun Wang, Jin Wu, Ketai He, Xiaoling Wang. The formation mechanism of Bacillus subtilis biofilm surface morphology under competitive environment. March 2023 Canadian Journal of Microbiology. DOI: 10.1139/cjm-2023-0014
2.Xianyong Li, Rui Kong, Jiankun Wang, Jin Wu, Xiaoling Wang. Matrix Producing Cells Induce the Morphological Difference in the Bacillus subtilis Biofilm. March 2023 Indian Journal of Microbiology. DOI: 10.1007/s12088-023-01073-w
3.Xiaoling Wang, Raphael Blumenfeld, Xiqiao Feng, David A. Weitz. ‘Phase transitions’ in bacteria – From structural transitions in free living bacteria to phenotypic transitions in bacteria within biofilms. Physics of Life Reviews. 2022, 43, 98-138. https://doi.org/10.1016/j.plrev.2022.09.004
4.Fulin Dong, Song Liu, Duohuai Zhang, Jinchang Zhang, Xiaoling Wang. Matrix-producing cells formed ‘Van Gogh bundles’ facilitate Bacillus subtilis biofilm self-healing. Environmental Microbiology Reports. 17 May 2022. DOI: 10.1111/1758-2229.13099
5.Jiankun Wang, Xianyong Li, Rui Kong, Jin Wu, Xiaoling Wang. Fractal morphology facilitates Bacillus subtilis biofilm growth. Environmental Science and Pollution Research. 15 March 2022. DOI: 10.1007/s11356-022-19817-4
6.JinChang Zhang, Song Liu, Fulin Dong, Duohuai Zhang, Xiaoling Wang. Biofilm streamer growth dynamics in various microfluidic channels. Canadian Journal of Microbiology. 22 January 2022. DOI: 10.1139/cjm-2021-0346
7.Song Liu, Fulin Dong, Duohuai Zhang, Jinchang Zhang, Xiaoling Wang. Effect of microfluidic channel geometry on Bacillus subtilis biofilm formation. Biomedical Microdevices. 18 January 2022. 24 (1), 1-11. DOI: 10.1007/s10544-022-00612-4
8.Fulin Dong, Song Liu, Duohuai Zhang, Jinchang Zhang, Xiaoling Wang, Hui Zhao. Osmotic Pressure Induced by Extracellular Matrix Drives Bacillus Subtilis Biofilms’ Self-healing. Computational Biology and Chemistry. 15 January 2022. 97:107632. DOI: 10.1016/j.compbiolchem.2022.107632
9.Xiaoling Wang, Fulin Dong, Jiali Liu, Yifan Tan, Shuaishuai Hu, Hui Zhao. The self‑healing of Bacillus subtilis bioflms. Archives of Microbiology. 31 August 2021. https://doi.org/10.1007/s00203-021-02542
10.Shuaishuai Hu, Xiaoling Wang, Yifan Tan, Jiali Liu, Hui Zhao. ‘Chain and running’ induced by mechanical interactions among cells of different phenotypes in the Bacillus subtilis biofilm. European Biophysics Journal. 2021, 50: 1013–1023. https://doi.org/10.1007/s00249-021-01562-0
11.Xiaoling Wang, Duohuai Zhang, Fulin Dong, Song Liu, Jinchang Zhang, Hui Zhao. Cell differentiation and motion determine the Bacillus subtilis biofilm morphological evolution under the competitive growth. Journal of Basic Microbiology 2021, 61(5), 396-405.
12.Xiaoling Wang, Yifan Tan, JiaLi Liu, Shuaishuai Hu, Hui Zhao. The Evolving Wrinkle Pattern of The Bacillus Subtilis Biofilm Providing More Living Space for Cells. Journal of Mechanics in Medicine and Biology. 2020, 20 (7), 2050048.
13.Xiaoling Wang, Yuhao Kong, Hui Zhao and Xiaoqiang Yan. Dependence of the Bacillus subtilis biofilm expansion rate on phenotypes and the morphology under different growing conditions. Development Growth and Regeneration. September 2019, 61, (7-8), 431-443. DOI: 10.1111/dgd.12627
14.Hui Zhao, Xuan Li, Wencheng Wang, Xiaoling Wang, Shaodong Wang, Na Lei, Xiangfeng Gu. Polycube Shape Space. Pacific Graphics 2019, 2019, 38 (7), 1-12.
15.Xiaoling Wang, Zhaocan Wang, Xing Shen, Yuhao Kong, Hui Zhao, Xiaoqiang Yan. Studying the internal stress heterogeneity of the growing biofilm by the micropillar deformation of the growing substrate. Journal of Mechanics in Medicine and Biology. 2019, 19(06), 1950070. DOI: 10.1142/S0219519419500702
16.Xiaoling Wang, Xing Shen, Zhaocan Wang, Yuhao Kong. Viscoelasticity variation in a biofilm-mediated Bacillus subtilis suspension induced by adding polyethylene glycol. European Biophysics Journal, 2019, 48(7), 599-608. DOI 10.1007/s00249-019-01385-0
17.Hui Zhao, Kehua Su, Chenchen Li, Boyu Zhang, Lei Yang, Na Lei, Xiaoling Wang, Steven J. Gortler, Xianfeng Gu. Mesh Parameterization Driven by Unit Normal Flow. COMPUTER GRAPHICS Forum 2019. https://doi.org/10.1111/cgf.13660
18.Hui Zhao, Xuan Li, Huabin Ge, Na Lei, Min Zhang, Xiaoling Wang, Xianfeng Gu. Conformal mesh parameterization using discrete Calabi flow. Computer Aided Geometric Design 2018, 63, 96-108. DOI: 10.1016/j.cagd.2018.03.001
19.Xiaoling Wang, Kai Zhao and Hui Zhao. Finite Element Simulation of Biofilm Viscoelastic Behavior under Various Loadings. Journal of Mechanics in Medicine and Biology. 2018, 18(5), 1850056. DOI: 10.1142/S0219519418500562
20.Siddarth Srinivasan, Ioana D. Vladescu, Stephan A. Koehler, Xiaoling Wang, Madhav Mani, and Shmuel M. Rubinstein. Matrix Production and Sporulation in Bacillus subtilis Biofilms Localize to Propagating Wave Fronts. Biophysical Journal 114, 1–9, March 27, 2018. https://doi.org/10.1016/j.bpj.2018.02.002
21.Cheng Zhang, Bo Li, Jing-Ying Tang, Xiaoling Wang, Zhao Qin and Xi-Qiao Feng. Experimental and theoretical studies on the morphogenesis of bacterial biofilms. Soft Matter. September 2017, 13, 7389-7397. DOI:10.1039/C7SM01593C
22.Xiaoling Wang, Shuo Meng and Jingshi Han. A Continuum Theoretical Model and Finite Elements Simulation of Bacterial Flagellar Filament Phase Transition. Journal of Biomechanics. October 2017, 63 (3), 21-31. DOI: http://dx.doi.org/10.1016/j.jbiomech.2017.09.012
23.Xiaoling Wang, Shuo Meng and Jingshi Han. Morphologies and phenotypes in Bacillus subtilis biofilms. Journal of Microbiology. August 2017, 55 (8), 619-627. DOI 10.1007/s12275-017-7041-z
24.Xianlong Zhang, Xiaoling Wang, Qingping Sun. Modeling of Biofilm Growth on Ager Substrate Using the Extended Finite Element Method. Procedia IUTAM. 2017 (23), 33-41. doi: 10.1016/j.piutam.2017.06.003
25.Xianlong Zhang, Xiaoling Wang, Kai Nie, Mingpeng Li, Qingping Sun. Simulation of Bacillus subtilis biofilm growth on agar plate by diffusion–reaction-based continuum model. Physical Biology. July 2016, 13 (4): 046002. DOI: 10.1088/1478-3975/13/4/046002
26.Jun-ichi Matsushita, Tatsuki Satsukawa, Naoya Iwamoto, Xiaoling Wang, Jianfeng Yang, Tomoyo Goto, Tohru Sekino, Xiaoyong Wu, Shu Yin, and Tsugio Sato. Oxidation of Pentatitanium Trisilicide (Ti5Si3) Powder at High Temperature. Materials Science Forum. 2016, 868, 38-42. DOI: 10.4028/www.scientific.net/MSF.868.38
27.Xiaoling Wang, Mudong Hao, Xin Du, Guoqing Wang, Junichi Matsushita. The mechanical analysis of the biofilm streamer nucleation and geometry characterization in microfluidic channels. Computational and Mathematical Methods in Medicine. 2016: 1-10. http://dx.doi.org/10.1155/2016/7819403.
28.Xiaoling Wang, Stephan A. Koehler, James N. Wilking，Naveen N. Sinha, Matthew T. Cabeen, Siddarth Srinivasan, Agnese Seminara, Shmuel Rubinstein, Qingping Sun, Michael P. Brenner, David A. Weitz. Probing Phenotypic growth in expanding Bacillus subtilis biofilms, Applied Microbiology and Biotechnology, 2016, 100(10), 4607-4615. DOI: 10.1007/s00253-016-7461-4.
29.Xiaoling Wang, Jingshi Han, Kui Li, Guoqing Wang and Mudong Hao, Multi-Layer composite mechanical modeling for the inhomogeneous biofilm mechanical behavior. Computational Biology and Chemistry. 2016, 14(4), 1650014-(1-14). DOI: http://dx.doi.org/10.1142/S0219720016500141
30.Jun-ichi Matsushita, Tomoyuki Tsuchiyama, Kazuya Hamaguchi, Naoya Iwamoto, Xiaoling Wang, Jianfeng Yang, Tohru Sekino, Xiaoyong Wu, Shu Yin, and Tsugio Sato. Anatase Type Titanium Dioxide Prepared by Oxidation of Titanium Carbide. Materials Science Forum, 2016, Vol. 860, 92-96. DOI: 10.4028/www.scientific.net/MSF.860.92
31.Xiaoling Wang, Mudong Hao and Guoqing Wang, Numerical simulation of wrinkle morphology formation and the evolution of different Bacillus subtilis biofilms. Water Science and Technology. 2016, 73(3), 527-534. DOI: 10.2166/wst.2015.486
32.Xiaoling Wang, Yingrui Hou, Guoqing Wang, Mudong Hao and Hao Li. Parametric Optimization of Metal Conductors in Flexible Electronics Design. Circuit World. 2016, Vol.42 (2), 89-94. DOI:10.1108/CW-08-2015-0043
33.Liang Dong, Runhua Zhou, Xiaoling Wang, Gengkai Hu, Qingping Sun. On interfacial energy of macroscopic domains in polycrystalline NiTi shape memory alloys. International Journal of Solids and Structures. 2016, 80, 445-455.
34.Xiaoling Wang, Guoqing Wang and Mudong Hao. Modeling of the Bacillus subtilis Bacterial Biofilm Growing on an Agar Substrate, Computational and Mathematical Methods in Medicine. 2015, 9, 1-10. DOI:10.1155/2015/581829
35.Xiaoling Wang, Hao Li and Guoqing Wang. Effect of the geometric parameters of elastomer substrates on the flexibility of stretchable electronics, Chinese Journal of Engineering, 2015, 37 (s1), 24-28
36.Xiaoling Wang, and Qingping. Sun. Modeling of rate-dependent phase transition in bacterial flagellar filament. Materials Research Bulletin, Materials Research Bulletin, 2013, 43, 5019-5025. DOI: 10.1016/j.materresbull.2013.05.009.
37.Xiaoling Wang, QingPing Sun. Mechanical modeling of the bistable bacterial flagellar filament. Acta Mech Solida Sinica, 2011. 24(S), 1-16.
38.Xiaoling Wang, Yongjun He, QingPing Sun. Simulation of Bacterial flagellar phase transition by non-convex and non-local continuum modeling. Theoretical & Applied Mechanics Letters. 2011, 1 (4): 044001-6.
39.Xiaoling Wang, QingPing Sun. Mechanical Analysis of Phase Transition Experiments of the Bacterial Flagellar Filament. Acta mechanica Sinica, 2010, 26 (5), 777-785.
40.Xiaoling Wang, QingPing Sun. The review of phase transition in biological systems. Advances in Mechanics, 2010 ,40 (1): 64-80 (in Chinese).
41.Xiaoling Wang, GengKai Hu. Stress transfer for a SMA fiber pulled out from an elastic matrix and related bridging effect. Composites part A - Applied Science and Manufacturing, 2005, 36 (8): 1142-1151.
42.Xiaoling Wang, Hui Zhao, Virtual Medical Model Modification with Laplacian System, International Conference on Biomedical Engineering & Informatics, 2010, 3(1), 1296-1299.
43.Xiaoling Wang, Qiang Zhang, The Mechanical Property Analysis of Circular Saw Blades under Different Rotational Speeds, Advanced Materials Research, 2010, 145, 365-370.
44.Xiaoling Wang, Yong Zhang, The Analysis on Different Circular Saw Structures for Reducing Saw Noise, Advanced Materials Research. 2010, 145, 551-556.
45.Xiaoling Wang, Hui Zhao, Surface Based Virtual Mechanical Equipment Modification, Advanced Materials Research, 2010, 149, 693-697.
46.Xiaoling Wang, Hui Zhao, Virtual Mechanical Equipment Model Smoothing, Advanced Materials Research, 2010, 156, 355-359.
47.Xiaoling Wang, Zhongjun Yin and Yanlin Li, The stress analysis of different circular saw structures during cutting, Advanced Materials Research. 2011, 228, 471-476.
48.Xiaoling Wang, Zhongjun Yin and Chao Zhang, The analysis of dynamic characteristics in reduction of the circular saw idling noise, Advanced Materials Research, 2011, 229, 477-483.
49.Xiaoling Wang, Zhongjun Yin and Chao Zhang, The mechanical analysis of the composite reinforced circular saw blade, Advanced Materials Research, 2011, 228: 484-489.

专利：
1.王晓玲*; 戴维A·韦茨; 一种实时观测枯草芽孢杆菌生物膜生长过程中不同基因表现型细胞和分布的方法, 2018-2-24, 中国, 201510388619.9.
2.王晓玲*; 戴维A·韦茨; 一种采用液滴微流控技术提高微生物燃料电池的输出功率的实验方法, 2017-05-27, 中国, 201510388861.6.